ADAPTIVE IMMUNITY, LEUKEMIA, AND OTHER BLOOD CELL PATHOLOGIES

Objectives:

1. Explain Adaptive Immunity and how it works to protect the body

2. Describe Leukemia (common types and common causes)

3. Describe Neutropenia. Explain some common causes

4. Explain Infectious Mononucleosis

5. Describe Lymphoma (common types and common causes)

6. Describe the characteristics of Multiple Myeloma

Vocabulary:

• Active Artificial Immunity
• Active Natural Immunity
• Adaptive Immunity
• ALL, AML, CLL, CML
• Antibody-dependent cell-mediated cytotoxicity (ADCC)
• Antigen
• Antigen presenting cell (APC)
• Autoimmunity
• B-cell
• Bence-Jones proteins
• Benign Ethnic Neutropenia
• Cytotoxic T cells (CD8+)
• Cords of Billroth
• Delayed type hypersensitivity (DTH)

• Epitope
• Erythropoietin (EPO)
• Fab region
• Fc region
• Felty syndrome
• Hapten
• Helper T cells (CD4+)
• Hematopoiesis
• Heterophile antibodies
• Human leukocyte antigens (HLA)
• Humoral Immunity
• Hypersensitivities (4 types)
• IgA, D, E, G, M
• Immunogen
• Kostman’s syndrome
• Leukemia
• Leukostasis
• Lymphoma
• MALT

• MHC I
• MHC II
• Mononucleosis
• M-spike
• Multiple Myeloma
• Neutropenia
• Opsonization
• Passive Artificial Immunity
• Passive Natural Immunity
• Philadelphia Chromosome
• Plasma Cell
• Plasmacytosis
• T-cell
• Thrombopoietin (TPO)
• Thymic Selection (positive and negative)